Downstream synthetic route of 99395-88-7

As the paragraph descriping shows that 99395-88-7 is playing an increasingly important role.

99395-88-7, (S)-4-Phenyloxazolidin-2-one is a oxazolidine compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

General procedure: To (4S)-4-phenyl-l,3-oxazolidin-2-one (10) (0.405 g, 2.48 mmol, 1 equiv) in DCM (3.00 mL) cooled to 0 C was added a solution of triethyloxonium tetrafluoroborate (1.41 g, 7.44 mmol, 3 equiv) in DCM (3.00 mL). The mixture was allowed to warm slowly to rt and stirred for 18 h. The mixture was diluted with EtOAc (20 mL) and poured slowly over a cooled (0 C) solution of saturated aqueous NaHCC (25 mL). The layers were separated, and the aqueous layer was extracted with EtOAc (2 x 20 mL). The combined organic layers were washed with brine, dried over Na2SC>4, filtered, and concentrated to afford (4S)-2-ethoxy-4-phenyl-4,5- dihydro-l,3-oxazole (17) (0.428 g, 90%): 1HNMR (CDC13) delta: 7.38-7.28 (m, 5H), 5.15 (dd, 1H), 4.47 (dd, 1H), 4.42-4.35 (m, 2H), 4.20 (t, 1H), 1.41 (t, 3H) ppm; MS: (m/e): 192 (M+l).

As the paragraph descriping shows that 99395-88-7 is playing an increasingly important role.

Reference£º
Patent; PURDUE PHARMA L.P.; BLAKE, Paul; TAFESSE, Laykea; (85 pag.)WO2017/192858; (2017); A1;,
Oxazolidine – Wikipedia
Oxazolidine | C3H7NO – PubChem