Brief introduction of (4S,5R)-4-Methyl-5-phenyloxazolidin-2-one

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In homogeneous catalysis, the catalyst is in the same phase as the reactant. The number of collisions between reactants and catalyst is at a maximum.In a patent, 16251-45-9, name is (4S,5R)-4-Methyl-5-phenyloxazolidin-2-one, introducing its new discovery. Recommanded Product: (4S,5R)-4-Methyl-5-phenyloxazolidin-2-one

SULFOXIMINE AND SULDODIIMINE MATRIX METALLOPROTEINASE INHIBITORS

Novel sulfoximine and sulfodiimine matrix metalloproteinase inhibitors of the formula, STR1 wherein: R 1 is selected from the group consisting of lower-alkyl, hydroxy lower-alkyl, amino lower-alkyl, carbamoyl lower-alkyl, lower-alkyl carbonyl, lower-alkyoxyalkyl, aralkyl and heteroaralkyl;

X is NH or O;

R 2 is selected from the group consisting of hydrogen, lower-alkyl and aralkyl;

R 3 is selected from the group consisting of hydrogen, lower-alkyl, amino lower-alkyl, guanyl lower-alkyl, aralkyl and heteroaralkyl; and

R 4 is selected from the group consisting of lower alkyl, aralkyl and–CH(R 5)–C(O)NH 2,

wherein R 5 is selected from the group consisting of hydrogen, lower-alkyl, amino lower-alkyl, guanyl lower-alkyl, imidazoylalkyl, hydroxymethyl, 1-hydroxyethyl, mercapto lower-alkyl, and methylthio lower-alkyl;

useful for modulating physiological functions or treating diseases and disease conditions associated with matrix metalloproteinase modulation.

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Reference£º
Oxazolidine – Wikipedia,
Oxazolidine | C3H2128NO – PubChem