Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments. Product Details of 497-25-6. Introducing a new discovery about 497-25-6, Name is Oxazolidin-2-one
Dialkylzinc mediated radical additions to chiral N-enoyloxazolidinones in the presence of benzaldehyde. Mechanistic investigation, structural characterization of the resulting gamma-lactones
Diethylzinc was used in the presence of oxygen to mediate radical additions to chiral N-enoyloxazolidinones derived from fumaric acid. The synthesis of sterically crowded trisubstituted gamma-lactones was achieved through a multicomponent reaction involving t-butyl iodide and benzaldehyde in addition to the above mentioned reagents. The domino process includes successively: iodine atom transfer, radical addition, homolytic substitution at zinc, aldol condensation, and lactonization. The diastereoselectivity of the reaction and the structural features of the resulting lactones were investigated. A tentative rationalization is discussed. Comparative experiments carried out with diisopropylzinc were performed.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.Product Details of 497-25-6, you can also check out more blogs about497-25-6
Reference£º
Oxazolidine – Wikipedia,
Oxazolidine | C3H340NO – PubChem