169048-83-3, Name is (S)-5-(Chloromethyl)oxazolidin-2-one, belongs to oxazolidine compound, is a common compound. Safety of (S)-5-(Chloromethyl)oxazolidin-2-oneIn an article, once mentioned the new application about 169048-83-3.
Enzymatic ammonolysis of ethyl (¡À)-4-chloro-3-hydroxybutanoate. Chemoenzymatic syntheses of both enantiomers of pyrrolidin-3-ol and 5- (chloromethyl)-1,3-oxazolidin-2-one
Lipase B from Candida antarctica efficiently catalysed the kinetic resolution of ethyl (¡À)-4-chloro-3-hydroxybutanoate through an ammonolysis reaction. Using this methodology, both enantiomers of 4-chloro-3- hydroxybutanamide were prepared and converted into pyrrolidin-3-ol and 5- (chloromethyl)-1,3-oxazolidin-2-one by simple processes consisting of a reduction reaction and a Hofmann rearrangement, respectively.
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Reference£º
Oxazolidine – Wikipedia,
Oxazolidine | C3H1397NO – PubChem