Chemistry can be defined as the study of matter and the changes it undergoes. category: oxazolidine. You’ll sometimes hear it called the central science because it is the connection between physics and all the other sciences, starting with biology.category: oxazolidine, Name is (R)-4-Benzyl-3-(3-methylbutanoyl)oxazolidin-2-one, molecular formula is C15H19NO3, introducing its new discovery.
We report a “macrocycle route” toward aliskiren, a drug presently marketed for the treatment of hypertension, using a highly stereocontrolled approach starting from a common “isopropyl chiron”. Highlights of the synthesis include a challenging RCM reaction to produce a nine-membered unsaturated lactone, a highly stereoselective catalytic Du Bois aziridination, and a regio- and diastereoselective aziridine ring-opening to a vicinal amino alcohol.
Keep reading other articles of 145589-03-3! Don’t worry, you don’t need a PhD in chemistry to understand the explanations!
Reference：
Oxazolidine – Wikipedia,
Oxazolidine | C3H2597NO – PubChem