Day: November 21, 2022

Shimoda, Mitsuya published the artcileHeadspace gas analysis of volatile compounds of light and deep roasted sesame seed oil, Application In Synthesis of 20662-83-3, the publication is Food Science and Technology International, Tokyo (1998), 4(1), 14-17, database is CAplus.

Volatile compounds in the headspace gas of light and deep roasted sesame seed oil were analyzed by gas chromatog. and gas chromatog.-mass spectrometry. The present method resulted in good reproducibility (<6.6% as a relative standard deviation) in the determination of individual volatile components. About 64 compounds, including 30 heterocyclic compounds, 7 aliphatic aldehydes, 11 ketones, and 16 miscellaneous compounds, were identified. Peak area percentages of 2-methylpropanal, 2-butenal, 2- and 3-methylbutanal, 2-propanone, 2-butanone, 3-methyl-2-butanone, 2,3-butanedione, 2- and 3-methylfuran, and 2,5-dimethylfuran, all of which could not be detected by steam distillation and column adsorptive concentration (previous method), increased in deep roasted oil. Hexanal decreased from 6.13% to 2.55% in deep roasted oil. Compared with the previous method, pyridine, thiophenes, and sulfides could be detected only by the present method, but unsaturated aliphatic aldehydes could not.

Food Science and Technology International, Tokyo published new progress about 20662-83-3. 20662-83-3 belongs to oxazolidine, auxiliary class Oxazole, name is 4,5-Dimethyloxazole, and the molecular formula is C5H5ClO2, Application In Synthesis of 20662-83-3.

Referemce:
https://en.wikipedia.org/wiki/Oxazolidine,
Oxazolidine | C3H7NO – PubChem

Whitfield, Frank B. published the artcileHeterocyclic Volatiles Formed by Heating Cysteine or Hydrogen Sulfide with 4-Hydroxy-5-methyl-3(2H)-furanone at pH 6.5, SDS of cas: 20662-83-3, the publication is Journal of Agricultural and Food Chemistry (2001), 49(2), 816-822, database is CAplus and MEDLINE.

The reaction of 4-hydroxy-5-methyl-3(2H)-furanone (HMF) with cysteine or H₂S at pH 6.5 for 60 min at 140 °C produced complex mixtures of volatile compounds, the majority of these containing either sulfur or nitrogen. Of the 68 compounds detected, 63 were identified, some tentatively, by GC-MS. Among the identified compounds were thiophenes (10), thiophenones (6), thienothiophenes (5), thiazoles (5), trithiolanes (4), pyrazines (6), and oxazoles (4). More compounds were produced in the reaction of HMF with cysteine (63) than were formed in the reaction with hydrogen sulfide (33). In both systems, thiophenones were the major reaction products, accounting for 25-36% of the total volatiles formed. Possible reasons for the differences in the composition of the 2 systems are discussed. The contributions of these reactions, and their products, to the flavor of heated foods are considered.

Journal of Agricultural and Food Chemistry published new progress about 20662-83-3. 20662-83-3 belongs to oxazolidine, auxiliary class Oxazole, name is 4,5-Dimethyloxazole, and the molecular formula is C11H15NOS, SDS of cas: 20662-83-3.

Referemce:
https://en.wikipedia.org/wiki/Oxazolidine,
Oxazolidine | C3H7NO – PubChem

Takahashi, K. published the artcileStructure of oxazolomycin, a new β-lactone antibiotic, Quality Control of 72571-06-3, the publication is Tennen Yuki Kagobutsu Toronkai Koen Yoshishu (1983), 189-96, database is CAplus.

Oxazolomycin (I) [89808-64-0] is a new antitumor antibiotic isolated from Streptomyces sp. (Y-32026). The structural elucidation of this noncrystalline antibiotic has been carried out. Its structure has been determined as I on the basis of spectral anal., x-ray crystallog. anal. and the synthesis of corresponding degraded products. The structure-biol. activity relationship was also studied. In vitro direct cytotoxicity of oxazole derivatives and each segment of oxazolomycin were examined

Tennen Yuki Kagobutsu Toronkai Koen Yoshishu published new progress about 72571-06-3. 72571-06-3 belongs to oxazolidine, auxiliary class Oxazole,Bromide,Benzene, name is 5-(4-Bromophenyl)oxazole, and the molecular formula is C6H12N2O, Quality Control of 72571-06-3.

Referemce:
https://en.wikipedia.org/wiki/Oxazolidine,
Oxazolidine | C3H7NO – PubChem

Boger, Dale L. published the artcileDiscovery of a Potent, Selective, and Efficacious Class of Reversible α-Ketoheterocycle Inhibitors of Fatty Acid Amide Hydrolase Effective as Analgesics, Recommanded Product: 4,5-Dimethyloxazole, the publication is Journal of Medicinal Chemistry (2005), 48(6), 1849-1856, database is CAplus and MEDLINE.

Fatty acid amide hydrolase (FAAH) degrades neuromodulating fatty acid amides including anandamide (endogenous cannabinoid agonist) and oleamide (sleep-inducing lipid) at their sites of action and is intimately involved in their regulation. Herein the authors report the discovery of a potent, selective, and efficacious class of reversible FAAH inhibitors that produce analgesia in animal models validating a new therapeutic target for pain intervention. Key to the useful inhibitor discovery was the routine implementation of a proteomics-wide selectivity screen against the serine hydrolase superfamily ensuring selectivity for FAAH coupled with systematic in vivo examinations of candidate inhibitors.

Journal of Medicinal Chemistry published new progress about 20662-83-3. 20662-83-3 belongs to oxazolidine, auxiliary class Oxazole, name is 4,5-Dimethyloxazole, and the molecular formula is C5H7NO, Recommanded Product: 4,5-Dimethyloxazole.

Referemce:
https://en.wikipedia.org/wiki/Oxazolidine,
Oxazolidine | C3H7NO – PubChem

Ukaji, Yutaka published the artcileAsymmetric bis(alkoxycarbonylation) reaction of homoallylic alcohols catalyzed by palladium in the presence of Cu(I) triflate using the chiral bioxazoline ligand, HPLC of Formula: 138429-17-1, the publication is Bulletin of the Chemical Society of Japan (1996), 69(3), 735-42, database is CAplus.

Palladium-catalyzed asym. intra- and intermol. bis(alkoxycarbonylation) reactions of homoallylic alcs. in the presence of copper(I) triflate were achieved by using the chiral bioxazoline ligand, (S,S)-4,4′-bis(phenylmethyl)-4,4′,5,5′-tetrahydro-2,2′-bioxazole, under normal pressure of carbon monoxide and oxygen at 25 °C to give the corresponding optically active γ-butyrolactones in 19-65% ee. For example, the allyl palladiumchloride dimer-catalyzed alkoxycarbonylation of 1-(2-propenyl)cyclohexanol (I) in the presence of trifluoromethanesulfonic acid copper(1+) salt (benzene solvate) and [S-(R*,R*)]-4,4′,5,5′-tetrahydro-4,4′-bis(phenylmethyl)-2,2-bioxazole in THF gave (S)-2-oxo-1-oxaspiro[4.5]decane-3-acetic acid Me ester (II) in 57% yield and in 65% enantiomeric excess.

Bulletin of the Chemical Society of Japan published new progress about 138429-17-1. 138429-17-1 belongs to oxazolidine, auxiliary class BOX Ligands, name is (4S,4’S)-4,4′-Diisobutyl-4,4′,5,5′-tetrahydro-2,2′-bioxazole, and the molecular formula is C4H6BrFO2, HPLC of Formula: 138429-17-1.

Referemce:
https://en.wikipedia.org/wiki/Oxazolidine,
Oxazolidine | C3H7NO – PubChem

Narziss, L. published the artcileVolatile substances formed during malt and beer production, especially those formed by heating the product. Part 1. Analysis, identification and effects on aroma, Application of 4,5-Dimethyloxazole, the publication is Monatsschrift fuer Brauwissenschaft (1988), 41(9), 344-52, database is CAplus.

The N-containing heterocyclic compounds in malt and beer were extracted and determined by gas chromatog. They were analyzed at a sniffing port as they came off the gas chromatograph, and the aroma of many of the substances was described.

Monatsschrift fuer Brauwissenschaft published new progress about 20662-83-3. 20662-83-3 belongs to oxazolidine, auxiliary class Oxazole, name is 4,5-Dimethyloxazole, and the molecular formula is C5H7NO, Application of 4,5-Dimethyloxazole.

Referemce:
https://en.wikipedia.org/wiki/Oxazolidine,
Oxazolidine | C3H7NO – PubChem

Belaidi, Salah published the artcileElectronic structure and physical-chemistry property relationship for oxazole derivatives by ab initio and DFT methods, Category: oxazolidine, the publication is Organic Chemistry International (2011), 254064, 7 pp., database is CAplus.

The geometric, electronic structure, effect of the substitution, and structure phys.-chem. relationship for oxazoles derivatives have been studied by ab initio and DFT theory. In the present work, the calculated values, namely, net charges, bond lengths, dipole moments, electron affinities, heats of formation, and QSPR properties are reported and discussed in terms of the reactivity of oxazole derivatives

Organic Chemistry International published new progress about 20662-83-3. 20662-83-3 belongs to oxazolidine, auxiliary class Oxazole, name is 4,5-Dimethyloxazole, and the molecular formula is C5H7NO, Category: oxazolidine.

Referemce:
https://en.wikipedia.org/wiki/Oxazolidine,
Oxazolidine | C3H7NO – PubChem

Kondrat’eva, G. Ya. published the artcileReaction of oxazoles with dienophiles of methylenemalonic ester type, Safety of 4,5-Dimethyloxazole, the publication is Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya (1972), 2125-6, database is CAplus.

Oxazoles (I) reacted with dienophiles e.g. CH:C-(CO2Et)2 (II) by 1,4-cycloaddition to give 25-40 adduct (III, R1 = PrO, BuO, Me; R2 = H, Me; R3 = CO2Et, Ac). All the dienophiles tried reacted with I (R1 = alkoxy), but I (R1 = Me) reacted with II only. I (R = PrO) and piperidinylcyclo-pentene reacted similarly to give 26 1:1 adduct. II were stable in storage or when heated to 200°.

Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya published new progress about 20662-83-3. 20662-83-3 belongs to oxazolidine, auxiliary class Oxazole, name is 4,5-Dimethyloxazole, and the molecular formula is C5H7NO, Safety of 4,5-Dimethyloxazole.

Referemce:
https://en.wikipedia.org/wiki/Oxazolidine,
Oxazolidine | C3H7NO – PubChem

Belaidi, Salah published the artcileElectronic structure and effect of methyl substitution in oxazole and thiazole by quantum chemical calculations, Related Products of oxazolidine, the publication is Research Journal of Pharmaceutical, Biological and Chemical Sciences (2014), 5(3), 811-818, database is CAplus.

Geometric and electronic structure of oxazole and thiazole and the effect of Me group substitution in thiazole and oxazole have been studied by PM3, ab initio method and d. functional Theory. In the present work, the calculated values, namely net charges, bond length, dipole moments, ionization potentials, electron-affinities and heats of formation are reported and discussed in terms of the reactivity of oxazole and thiazole systems.

Research Journal of Pharmaceutical, Biological and Chemical Sciences published new progress about 20662-83-3. 20662-83-3 belongs to oxazolidine, auxiliary class Oxazole, name is 4,5-Dimethyloxazole, and the molecular formula is C5H7NO, Related Products of oxazolidine.

Referemce:
https://en.wikipedia.org/wiki/Oxazolidine,
Oxazolidine | C3H7NO – PubChem

Han, Wei published the artcilePalladium-Catalyzed Dehydrogenative Cross-Couplings of Benzazoles with Azoles, Category: oxazolidine, the publication is Angewandte Chemie, International Edition (2011), 50(9), 2178-2182, S2178/1-S2178/58, database is CAplus and MEDLINE.

Unsym. 2,2′-bisheteroaryls are prepared by regioselective C-C coupling between the nonfunctionalized C2 positions of azoles through the cleavage of two C-H bonds. E.g., in the presence of Pd(OAc)₂, Cu(OAc)₂.H₂O, KF, and AgNO₃ under a normal air atm., coupling of benzothiazole and 1-methylimidazole gave 91% 2-(1-methyl-1H-imidazol-2-yl)benzothiazole (I). Formation of homocoupling products was suppressed by the presence of Ag⁺ ions.

Angewandte Chemie, International Edition published new progress about 72571-06-3. 72571-06-3 belongs to oxazolidine, auxiliary class Oxazole,Bromide,Benzene, name is 5-(4-Bromophenyl)oxazole, and the molecular formula is C9H6BrNO, Category: oxazolidine.

Referemce:
https://en.wikipedia.org/wiki/Oxazolidine,
Oxazolidine | C3H7NO – PubChem