Day: November 21, 2022

Bowie, J. H. published the artcileElectron impact studies. XXIII. Mass spectra of some alkyl and aryl oxazoles, Formula: C5H7NO, the publication is Organic Mass Spectrometry (1968), 1(1), 13-29, database is CAplus.

The mass spectra of a variety of alkyl and aryl oxazoles have been determined and the spectra analyzed with the aid of D labeling and high resolution mass spectrometry. In contrast to the corresponding benzenoid compounds, the mass spectra of isomeric alkyl oxazoles are distinctive and in this respect are akin to those of the corresponding pyridines. Further analogy to the pyridines is suggested by the unfavorable nature of a carbonium ion adjacent to the 2-position and this effect may be used to locate alkyl substituents attached to the oxazole nucleus. The loss of CO from the mol. ions of 2,5-disubstituted oxazoles probably occurs with ring opening and migration of the C-5 substituent (e.g., Br) to the C-4 position. 22 references.

Organic Mass Spectrometry published new progress about 20662-83-3. 20662-83-3 belongs to oxazolidine, auxiliary class Oxazole, name is 4,5-Dimethyloxazole, and the molecular formula is C5H7NO, Formula: C5H7NO.

Referemce:
https://en.wikipedia.org/wiki/Oxazolidine,
Oxazolidine | C3H7NO – PubChem

Liu, Wei published the artcileA Strategy for the Synthesis of Sulfonamides on DNA, Name: 5-(4-Bromophenyl)oxazole, the publication is Organic Letters (2019), 21(24), 9909-9913, database is CAplus and MEDLINE.

An efficient method is reported to synthesize sulfonamides on DNA from sulfinic acids or sodium sulfinates and amines in the presence of iodine under mild conditions. This method demonstrates a major expansion of scope of sulfonamide formation on DNA through the utilization of a novel sodium carbonate-sodium sulfinate bifunctional reagent class.

Organic Letters published new progress about 72571-06-3. 72571-06-3 belongs to oxazolidine, auxiliary class Oxazole,Bromide,Benzene, name is 5-(4-Bromophenyl)oxazole, and the molecular formula is C9H6BrNO, Name: 5-(4-Bromophenyl)oxazole.

Referemce:
https://en.wikipedia.org/wiki/Oxazolidine,
Oxazolidine | C3H7NO – PubChem

Kim, Tae Sung published the artcileActivity of LCB01-0371, a novel oxazolidinone, against Mycobacterium abscessus, HPLC of Formula: 1219707-39-7, the publication is Antimicrobial Agents and Chemotherapy (2017), 61(9), e02752-16/1-e02752-16/12, database is CAplus and MEDLINE.

Mycobacterium abscessus is a highly pathogenic drug-resistant rapidly growing mycobacterium. In this study, we evaluated the in vitro, intracellular, and in vivo activities of LCB01-0371, a novel and safe oxazolidinone derivative, for the treatment of M. abscessus infection and compared its resistance to that of other oxazolidinone drugs. LCB01-0371 was effective against several M. abscessus strains in vitro and in a macrophage model of infection. In the murine model, a similar efficacy to linezolid was achieved, especially in the lungs. We induced laboratory-generated resistance to LCB01-0371; sequencing anal. revealed mutations in rplC of T424C and G419A and a nucleotide insertion at the 503 position. Furthermore, LCB01-0371 inhibited the growth of amikacin-, cefoxitin-, and clarithromycin-resistant strains. Collectively, our data indicate that LCB01-0371 might represent a promising new class of oxazolidinones with improved safety, which may replace linezolid for the treatment of M. abscessus.

Antimicrobial Agents and Chemotherapy published new progress about 1219707-39-7. 1219707-39-7 belongs to oxazolidine, auxiliary class Other Aliphatic Heterocyclic,Oxazolidine,Chiral,Fluoride,Benzene,Amide,Alcohol,Anti-infection, name is (R)-3-(3-Fluoro-4-(1-methyl-5,6-dihydro-1,2,4-triazin-4(1H)-yl)phenyl)-5-(hydroxymethyl)oxazolidin-2-one, and the molecular formula is C14H17FN4O3, HPLC of Formula: 1219707-39-7.

Referemce:
https://en.wikipedia.org/wiki/Oxazolidine,
Oxazolidine | C3H7NO – PubChem

Yang, Ruiyang published the artcileSynthesis and application of chiral bidentate N-donor ligands, 2,2′-bis(oxazolines), Category: oxazolidine, the publication is Huaxue Xuebao (1991), 49(10), 1038-40, database is CAplus.

The chiral bidentate ligands I (R = Me₂CH, PhCH₂, CH₂CHMe₂) were prepared from RCH(NH₂)CH₂OH by condensation with di-Et oxalate, chlorination with SOCL₂, and cyclization of the resulting chlorides II with MeONa. The use of I in asym. hydroxylation of PhCH:CHPh, PhCH:CH₂, and 1-phenlcyclohexene with OsO₄ was reported.

Huaxue Xuebao published new progress about 138429-17-1. 138429-17-1 belongs to oxazolidine, auxiliary class BOX Ligands, name is (4S,4’S)-4,4′-Diisobutyl-4,4′,5,5′-tetrahydro-2,2′-bioxazole, and the molecular formula is C10H10O6, Category: oxazolidine.

Referemce:
https://en.wikipedia.org/wiki/Oxazolidine,
Oxazolidine | C3H7NO – PubChem

Yang, Ke published the artcileCobalt-Catalyzed Decarboxylative 2-Benzoylation of Oxazoles and Thiazoles with α-Oxocarboxylic Acids, Recommanded Product: 5-(4-Bromophenyl)oxazole, the publication is Journal of Organic Chemistry (2015), 80(21), 11065-11072, database is CAplus and MEDLINE.

Cobalt-catalyzed decarboxylative cross-coupling of oxazoles and thiazoles with α-oxocarboxylic acids was developed through an sp² C-H bond functionalization process. This work represents the first example of cobalt-catalyzed decarboxylative C-H bond functionalization and provides an efficient means of building some important bioactive heteroaryl ketone derivatives

Journal of Organic Chemistry published new progress about 72571-06-3. 72571-06-3 belongs to oxazolidine, auxiliary class Oxazole,Bromide,Benzene, name is 5-(4-Bromophenyl)oxazole, and the molecular formula is C16H20N2, Recommanded Product: 5-(4-Bromophenyl)oxazole.

Referemce:
https://en.wikipedia.org/wiki/Oxazolidine,
Oxazolidine | C3H7NO – PubChem

Puvipirom, J. published the artcileContribution of roasted grains and seeds in aroma of oleang (Thai coffee drink), Application In Synthesis of 20662-83-3, the publication is International Food Research Journal (2012), 19(2), 583-588, database is CAplus.

Oleang, a Thai coffee drink, contained roasted robusta coffee and several roasted grains and seeds. In this research the typical ingredients of oleang that were robusta coffee, corn, soybean, rice, sesame and brown sugar, were roasted and studied for their volatile compounds Coffee, corn, sesame, and brown sugar were roasted at 220°C for 20 min and soybean and rice were roasted at 240°C for 20 min. Major aroma compounds from roasted com were 2-furfurylthiol, furfural, 2-methoxyphenol, hexanal, and alkylpyrazines. Soybean contributed mostly pyrazines and phenols similar to those of coffee. The roasted rice had strong sulfurous and burnt characteristics but was low in concentrations of the volatile compounds The roasted sesame was most abundant in the numbers of aroma compounds provided di-Me trisulfide, di-Me disulfide, 2-furfurylthiol, 3-ethyl-2,5-dimethylpyrazine, and 2-methoxyphenol to oleang. Sixteen oleang formulations were evaluated for their sensory preference. The samples were composed of 5% brown sugar, coffee (50, 60, 70, and 80%) with various corn: soybean: rice: sesame ratios (2:3:0:0, 3:2:0:0, 3:1:1:0, and 3:1:0:1). The most preferred formulation for oleang was 50% coffee, 5% brown sugar, and 45% grain mixture that had the corn: soybean: rice: sesame ratio of 3:1:1:0.

International Food Research Journal published new progress about 20662-83-3. 20662-83-3 belongs to oxazolidine, auxiliary class Oxazole, name is 4,5-Dimethyloxazole, and the molecular formula is C5H7NO, Application In Synthesis of 20662-83-3.

Referemce:
https://en.wikipedia.org/wiki/Oxazolidine,
Oxazolidine | C3H7NO – PubChem

Bianchi, Federica published the artcileComparison of comprehensive two-dimensional gas chromatography-time-of-flight mass spectrometry and gas chromatography-mass spectrometry for the qualitative characterisation of roasted barley by solid-phase microextraction, Name: 4,5-Dimethyloxazole, the publication is Journal of Separation Science (2007), 30(4), 527-533, database is CAplus and MEDLINE.

Volatile compounds of roasted barley used in the production of barley coffee, the most common coffee substitute, were analyzed by using solid-phase microextraction (SPME) followed by GC-MS and comprehensive GC × GC-TOF-MS, resp. The optimized SPME extraction conditions in terms of selection of the fiber coating, extraction time and extraction temperature allowed to obtain the highest GC response, thus enhancing the identification capabilities of the developed method. As for the SPME-GC × GC-TOF-MS anal., 64 compounds with similarity, reverse and probability values above 800, 900 and 6000, resp., were identified, by using a polar × apolar column set combination; in contrast, GC-MS was able to identify a lower number of compounds, i.e. 40 volatiles.

Journal of Separation Science published new progress about 20662-83-3. 20662-83-3 belongs to oxazolidine, auxiliary class Oxazole, name is 4,5-Dimethyloxazole, and the molecular formula is C5H7NO, Name: 4,5-Dimethyloxazole.

Referemce:
https://en.wikipedia.org/wiki/Oxazolidine,
Oxazolidine | C3H7NO – PubChem

Gu, Bo published the artcileCatalytic Fast Pyrolysis of Sewage Sludge over HZSM-5: A Study of Light Aromatics, Coke, and Nitrogen Migration under Different Atmospheres, Application of 4,5-Dimethyloxazole, the publication is Industrial & Engineering Chemistry Research (2020), 59(39), 17537-17545, database is CAplus.

catalytic fast pyrolysis of wastewater sludge was conducted to assess pyrolysis temperature and atm., and catalysts effect on C and N distribution in a fixed-bed reactor. a H₂ atmosphere had the lowest C selectivity of solid products and the highest gaseous product yield over HZSM-5 (HZ) at the same temperature vs. Ar and steam atmospheres. higher temperature led to increased C selectivity of gaseous products and decreased C selectivity of solids. H₂ increased the C yield of light aromatics (LA); steam reduced generation of LA. over 0.5 Ni-HZ, H₂ had the highest LA C yield (11.4%) vs. 1.6% from non-catalytic fast pyrolysis of sludge. higher temperatures, H₂ and steam atmospheres, and metal-loaded HZ promoted N transfer to gaseous products. the highest N yield (i.e., NH₃) of 55.6% was obtained from sludge pyrolysis over HZ at 700° in a H₂ atmosphere.

Industrial & Engineering Chemistry Research published new progress about 20662-83-3. 20662-83-3 belongs to oxazolidine, auxiliary class Oxazole, name is 4,5-Dimethyloxazole, and the molecular formula is C5H7NO, Application of 4,5-Dimethyloxazole.

Referemce:
https://en.wikipedia.org/wiki/Oxazolidine,
Oxazolidine | C3H7NO – PubChem

Xiang, Zhangmin published the artcileAnalysis of nitrogenous organic compounds from mainstream cigarette smoke using low-temperature solvent extraction followed by comprehensive two-dimensional gas chromatography with high-resolution time-of-flight mass spectrometry, Name: 4,5-Dimethyloxazole, the publication is Journal of Separation Science (2015), 38(15), 2655-2663, database is CAplus and MEDLINE.

A method involving comprehensive two-dimensional gas chromatog. coupled to high-resolution time-of-flight mass spectrometry was developed and applied to the anal. of nitrogenous organic compounds present in mainstream cigarette smoke trapped on self-designed equipment. The samples were prepared using low-temperature solvent extraction under liquid nitrogen and analyzed by comprehensive two-dimensional gas chromatog. with high-resolution time-of-flight mass spectrometry. Important exptl. parameters, such as the type and volume of the extraction solvent and flow rate of smoking, were optimized to improve the anal. parameter. The results indicated that 180 mL of di-Et ether in the low-temperature solvent extraction apparatus system with a 4 mL/min smoke flow rate were the optimal conditions. Then, 85 nitrogenous organic compounds were identified and quantified using a mass spectral library search, accurate mass ion and N-rules of a mol. formula for nitrogen compounds Finally, a comparison of the low temperature solvent extraction and Cambridge filter pad method indicated that more peaks, a higher peak volume and better repeatability were obtained using the low-temperature solvent extraction method.

Journal of Separation Science published new progress about 20662-83-3. 20662-83-3 belongs to oxazolidine, auxiliary class Oxazole, name is 4,5-Dimethyloxazole, and the molecular formula is C6H8N2, Name: 4,5-Dimethyloxazole.

Referemce:
https://en.wikipedia.org/wiki/Oxazolidine,
Oxazolidine | C3H7NO – PubChem

Oliveira, Alcilucia published the artcileIdentification and recovery of volatiles organic compounds (VOCs) in the coffee-producing wastewater, Name: 4,5-Dimethyloxazole, the publication is Journal of Water Resource and Protection (2014), 6(4), 375-380, 6 pp., database is CAplus.

The objectives of the present study were to recover and identify volatiles organic compounds (VOCs) in the wastewater (WW) coming from a soluble coffee industrial plant. For VOCs recover, the WW was concentrated by pervaporation using a polydimethylsiloxane (PDMS) membrane. Furthermore, the solid phase micro extraction (SPME) and gas chromatog.-mass spectrometry (GC-MS) were used for VOCs identification. The multivariate method of principal component anal. (PCA) was performed to evaluate differences amongst the feed and concentrate streams. Regarding the number of VOCs identified in the wastewater (33) and permeate (72), a significant statistical difference at p < 0.05 was observed Clusters discriminating were clearly observed, as the feed and permeate streams are compared. Thus, we can conclude that pervaporation process using a PDMS membrane was effective to recover different class of VOCs present in the aqueous effluent and can be recommended for industrial wastewater treatment.

Journal of Water Resource and Protection published new progress about 20662-83-3. 20662-83-3 belongs to oxazolidine, auxiliary class Oxazole, name is 4,5-Dimethyloxazole, and the molecular formula is C5H7NO, Name: 4,5-Dimethyloxazole.

Referemce:
https://en.wikipedia.org/wiki/Oxazolidine,
Oxazolidine | C3H7NO – PubChem