Day: November 10, 2022

Cp*rhodium complexes with salicyloxazolines: Diastereoselective synthesis, configurational stability and use as asymmetric catalysts for a Diels-Alder reaction was written by Davenport, Adam J.; Davies, David L.; Fawcett, John; Russell, David R.. And the article was included in Journal of Organometallic Chemistry on May 1,2006.COA of Formula: C11H13NO2 The following contents are mentioned in the article:

Reaction of [RhCl2Cp*]2 (Cp* = η-C5Me5) with appropriate salicyloxazolines in the presence of NaOMe gave 72-83% [RhCl(R,R’-saloxaz)Cp*] [R = R’ = Me (1); R = H, R’ = Me2CH (2), PhCH2 (3), Ph (4)] which were fully characterized; complexes 2-4 contain an enantiopure (S)-saloxaz ligand. The diastereoselectivity of complexation depends on the substituents and the absolute configuration at the metal center is unstable in solution Thus, salicyloxazoline ligands coordinate diastereoselectively to the Cp*RhCl fragment with the oxazoline substituent oriented towards the chloride except in the case of the Ph-substituted complex. Treatment of 2 with 4-methylpyridine and NaSbF6 in MeOH at reflux gave [Rh(4-Mepy){(S)-iPr-saloxaz}Cp*][SbF6] (5) while [Rh(OH2)(Me2-saloxaz)Cp*][SbF6] (6) was prepared by reaction of 1 with AgSbF6. Three complexes, [RhCl(Me2-saloxaz)Cp*] (1), [RhCl{(S)-iPr-saloxaz}Cp*] (2), and [Rh(OH2)(Me2-saloxaz)Cp*][SbF6] (6) were characterized by x-ray crystallog. Some of the complexes, after treatment with AgSbF6, were tested as enantioselective catalysts for the Diels-Alder reaction of methacrolein with cyclopentadiene, but gave much poorer results than the corresponding arene ruthenium complexes. This study involved multiple reactions and reactants, such as 2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)phenol (cas: 163165-91-1COA of Formula: C11H13NO2).

2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)phenol (cas: 163165-91-1) belongs to oxazolidine derivatives. Oxazolidines that are the precursor to bisoxazolidines are in effect mono-oxazolidines. They are also used as moisture scavengers in polyurethane and other systems. Chiral oxazolidines are widely used as chiral auxiliaries, chiral ligands, protecting and/or directing groups in a variety of asymmetric transformations, thanks also to their easy cleavage or their further elaboration possibilities.COA of Formula: C11H13NO2

163165-91-1;2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)phenol;The future of 163165-91-1;New trend of C11H13NO2;function of 163165-91-1

Cp*rhodium complexes with salicyloxazolines: Diastereoselective synthesis, configurational stability and use as asymmetric catalysts for a Diels-Alder reaction was written by Davenport, Adam J.; Davies, David L.; Fawcett, John; Russell, David R.. And the article was included in Journal of Organometallic Chemistry on May 1,2006.Electric Literature of C16H15NO2 The following contents are mentioned in the article:

Reaction of [RhCl2Cp*]2 (Cp* = η-C5Me5) with appropriate salicyloxazolines in the presence of NaOMe gave 72-83% [RhCl(R,R’-saloxaz)Cp*] [R = R’ = Me (1); R = H, R’ = Me2CH (2), PhCH2 (3), Ph (4)] which were fully characterized; complexes 2-4 contain an enantiopure (S)-saloxaz ligand. The diastereoselectivity of complexation depends on the substituents and the absolute configuration at the metal center is unstable in solution Thus, salicyloxazoline ligands coordinate diastereoselectively to the Cp*RhCl fragment with the oxazoline substituent oriented towards the chloride except in the case of the Ph-substituted complex. Treatment of 2 with 4-methylpyridine and NaSbF6 in MeOH at reflux gave [Rh(4-Mepy){(S)-iPr-saloxaz}Cp*][SbF6] (5) while [Rh(OH2)(Me2-saloxaz)Cp*][SbF6] (6) was prepared by reaction of 1 with AgSbF6. Three complexes, [RhCl(Me2-saloxaz)Cp*] (1), [RhCl{(S)-iPr-saloxaz}Cp*] (2), and [Rh(OH2)(Me2-saloxaz)Cp*][SbF6] (6) were characterized by x-ray crystallog. Some of the complexes, after treatment with AgSbF6, were tested as enantioselective catalysts for the Diels-Alder reaction of methacrolein with cyclopentadiene, but gave much poorer results than the corresponding arene ruthenium complexes. This study involved multiple reactions and reactants, such as (S)-2-(4-Benzyl-4,5-dihydrooxazol-2-yl)phenol (cas: 163165-92-2Electric Literature of C16H15NO2).

(S)-2-(4-Benzyl-4,5-dihydrooxazol-2-yl)phenol (cas: 163165-92-2) belongs to oxazolidine derivatives. Oxazolidines are commonly obtained by reaction of strained heterocycles, mainly aziridines. Oxazolidines are cyclic condensation products of β-amino alcohols and aldehydes or ketone, and they undergo a facile and complete hydrolysis in aqueous solution. Alterations in carbonyl moiety control the rate of formation of a given β-amino alcohol. Oxazolidines are weaker bases (pKa 6–7) than parent β-amino alcohols and found to be more lipophilic than the parent compound at physiological pH.Electric Literature of C16H15NO2

163165-92-2;(S)-2-(4-Benzyl-4,5-dihydrooxazol-2-yl)phenol;The future of 163165-92-2;New trend of C16H15NO2;function of 163165-92-2

Catalytic reduction of nitrate by an oxidorhenium (V) complex was written by Schachner, J. A.; Wiedemaier, F.; Zwettler, N.; Peschel, L. M.; Boese, A. D.; Belaj, F.; Moesch-Zanetti, N. C.. And the article was included in Journal of Catalysis on May 31,2021.Related Products of 163165-91-1 The following contents are mentioned in the article:

The previously published oxidorhenium(V) complex [ReOCl(L1)2] (2), equipped with the bidentate phenol-dimethyloxazoline ligand HL1 (2-(4,4-dimethyl-4,5-dihydro-1,3-oxazol-2-yl)-phenol), shows catalytic activity for the reduction of nitrate to nitrite under mild, ambient and aqueous conditions. The reaction operates under an oxygen atom transfer (OAT) mechanism, using di-Me sulfide SMe2 (DMS) as oxygen acceptor. Experiments with catalytic amounts of 2 and labeled 15NO-3 proved the full reduction of 15NO-3 to 15NO-2 by 15N NMR spectroscopy. For the second reduction step of nitrite NO-2, we have evidence for a single electron reduction to yield paramagnetic NO, as from one nitrate reduction experiment the paramagnetic cis-dioxidorhenium(VI) complex [Re(O)2(L1)2] (3) could be isolated and characterized by single-crystal X-ray diffraction anal. Such a single electron reduction of nitrite NO-2 would yield NO and complex 3 as the oxidation product. In a stoichiometric experiment of 2, 15NO-3 and DMS, nitrous oxide 15N2O could be detected as the only 15N containing product by 15N NMR spectroscopy, proving that further reduction beyond NO is possible with pre-catalyst 2. The rhenium species responsible for the reduction to N2O is currently unknown. Most likely, N2O is formed via an intermediate rhenium nitrosyl complex. Exptl. data was gathered by 1H and 15N NMR, IR- and UV-Vis spectroscopy, HR-ESI mass spectrometry, X-ray crystallog., and supported by theor. computations (DFT). This study involved multiple reactions and reactants, such as 2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)phenol (cas: 163165-91-1Related Products of 163165-91-1).

2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)phenol (cas: 163165-91-1) belongs to oxazolidine derivatives. Oxazolidine-based compounds have started to attract attention also in the medicinal and materials chemistry fields. Oxazolidines are cyclic condensation products of β-amino alcohols and aldehydes or ketone, and they undergo a facile and complete hydrolysis in aqueous solution. Alterations in carbonyl moiety control the rate of formation of a given β-amino alcohol. Oxazolidines are weaker bases (pKa 6–7) than parent β-amino alcohols and found to be more lipophilic than the parent compound at physiological pH.Related Products of 163165-91-1

163165-91-1;2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)phenol;The future of 163165-91-1;New trend of C11H13NO2;function of 163165-91-1

Oxazoline Early Transition Metal Complexes: Functionalizable Achiral Titanium(IV), Titanium(III), Zirconium(IV), Vanadium(III), and Chiral Zirconium(IV) Bis(oxazoline) Complexes was written by Cozzi, Pier Giorgio; Floriani, Carlo; Chiesi-Villa, Angiola; Rizzoli, Corrado. And the article was included in Inorganic Chemistry on May 24,1995.Formula: C11H13NO2 The following contents are mentioned in the article:

Large-scale syntheses of the (hydroxyphenyl)oxazoline ligands [I; R = R’ = Me, R” = H (L1); R = CH2Ph, R’ = R” = H (L2); R = CHMe2, R’ = R” = H (L3); R = Me, R’ = H, R” = Ph (L4); R = Ph, R’ = R” = H (L5)] are reported. The conversion of L1-L5 into the corresponding sodium salts was employed for metal complexation. The reaction of L1 with TiCl4·2THF, TiCl3·3THF, ZrCl4·2THF, and VCl3·3THF in a 1:2 metal:ligand ratio afforded the corresponding hexacoordinate functionalizable metal complexes: cis-[Cl2Ti(L1)2], 11; cis-[(THF)ClTi(L1)2], 12; cis-[Cl2Zr(L1)2], 13; trans-[(THF)ClV(L1)2], 14. The structures of 11, 12, and 14 were clarified by x-ray anal. The reaction of the L3 and L4 sodium salts with ZrCl4·2THF in a 1:2 metal:ligand ratio led to the corresponding chiral functionalizable metal complexes, whose structures were clarified by x-ray anal.: cis-[Cl2Zr(L3)2], 15; cis-[Cl2Zr(L4)2], 16. A common significant feature discovered from these studies is the existence of intramol. hydrogen bonding, which is probably responsible for the high conformational rigidity of the oxazoline ligand. Crystallog. details are as follows: 11 is monoclinic, space group I2/a, with a 16.443(2), b 8.365(1), c 17.945(2) Å, β 106.93(1)°, Z = 4, and R = 0.034; 12 is orthorhombic, space group Pca21, with a 15.669(2), b 17.750(3), c 18.971(3) Å, Z = 8, and R = 0.050; 14 is monoclinic, space group P21/n, with a 9.391(4), b 28.618(6), c 12.077(4) Å, β 105.79(2)°, Z = 4, and R = 0.052; 16 is monoclinic, space group P21, with a 10.161(2), b 14.151(3), c 12.361(2) Å, β 93.76(2)°, Z = 2, and R = 0.033. This study involved multiple reactions and reactants, such as 2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)phenol (cas: 163165-91-1Formula: C11H13NO2).

2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)phenol (cas: 163165-91-1) belongs to oxazolidine derivatives.Oxazolidines are readily available also from propargyl amines. Oxazolidines are cyclic condensation products of β-amino alcohols and aldehydes or ketone, and they undergo a facile and complete hydrolysis in aqueous solution. Alterations in carbonyl moiety control the rate of formation of a given β-amino alcohol.Formula: C11H13NO2

163165-91-1;2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)phenol;The future of 163165-91-1;New trend of C11H13NO2;function of 163165-91-1

Oxazoline Early Transition Metal Complexes: Functionalizable Achiral Titanium(IV), Titanium(III), Zirconium(IV), Vanadium(III), and Chiral Zirconium(IV) Bis(oxazoline) Complexes was written by Cozzi, Pier Giorgio; Floriani, Carlo; Chiesi-Villa, Angiola; Rizzoli, Corrado. And the article was included in Inorganic Chemistry on May 24,1995.Application In Synthesis of (S)-2-(4-Benzyl-4,5-dihydrooxazol-2-yl)phenol The following contents are mentioned in the article:

Large-scale syntheses of the (hydroxyphenyl)oxazoline ligands [I; R = R’ = Me, R” = H (L1); R = CH2Ph, R’ = R” = H (L2); R = CHMe2, R’ = R” = H (L3); R = Me, R’ = H, R” = Ph (L4); R = Ph, R’ = R” = H (L5)] are reported. The conversion of L1-L5 into the corresponding sodium salts was employed for metal complexation. The reaction of L1 with TiCl4·2THF, TiCl3·3THF, ZrCl4·2THF, and VCl3·3THF in a 1:2 metal:ligand ratio afforded the corresponding hexacoordinate functionalizable metal complexes: cis-[Cl2Ti(L1)2], 11; cis-[(THF)ClTi(L1)2], 12; cis-[Cl2Zr(L1)2], 13; trans-[(THF)ClV(L1)2], 14. The structures of 11, 12, and 14 were clarified by x-ray anal. The reaction of the L3 and L4 sodium salts with ZrCl4·2THF in a 1:2 metal:ligand ratio led to the corresponding chiral functionalizable metal complexes, whose structures were clarified by x-ray anal.: cis-[Cl2Zr(L3)2], 15; cis-[Cl2Zr(L4)2], 16. A common significant feature discovered from these studies is the existence of intramol. hydrogen bonding, which is probably responsible for the high conformational rigidity of the oxazoline ligand. Crystallog. details are as follows: 11 is monoclinic, space group I2/a, with a 16.443(2), b 8.365(1), c 17.945(2) Å, β 106.93(1)°, Z = 4, and R = 0.034; 12 is orthorhombic, space group Pca21, with a 15.669(2), b 17.750(3), c 18.971(3) Å, Z = 8, and R = 0.050; 14 is monoclinic, space group P21/n, with a 9.391(4), b 28.618(6), c 12.077(4) Å, β 105.79(2)°, Z = 4, and R = 0.052; 16 is monoclinic, space group P21, with a 10.161(2), b 14.151(3), c 12.361(2) Å, β 93.76(2)°, Z = 2, and R = 0.033. This study involved multiple reactions and reactants, such as (S)-2-(4-Benzyl-4,5-dihydrooxazol-2-yl)phenol (cas: 163165-92-2Application In Synthesis of (S)-2-(4-Benzyl-4,5-dihydrooxazol-2-yl)phenol).

(S)-2-(4-Benzyl-4,5-dihydrooxazol-2-yl)phenol (cas: 163165-92-2) belongs to oxazolidine derivatives. Oxazolidine-based compounds have started to attract attention also in the medicinal and materials chemistry fields. Oxazolidines are cyclic condensation products of β-amino alcohols and aldehydes or ketone, and they undergo a facile and complete hydrolysis in aqueous solution. Alterations in carbonyl moiety control the rate of formation of a given β-amino alcohol. Oxazolidines are weaker bases (pKa 6–7) than parent β-amino alcohols and found to be more lipophilic than the parent compound at physiological pH.Application In Synthesis of (S)-2-(4-Benzyl-4,5-dihydrooxazol-2-yl)phenol

163165-92-2;(S)-2-(4-Benzyl-4,5-dihydrooxazol-2-yl)phenol;The future of 163165-92-2;New trend of C16H15NO2;function of 163165-92-2

Syntheses and crystal structures of 4,5-dihydro-2-(2-hydroxyphenyl)oxazole-containing metal complexes was written by Bolm, Carsten; Weickhardt, Konrad; Zehnder, Margareta; Glasmacher, Dorothea. And the article was included in Helvetica Chimica Acta on June 19,1991.Formula: C13H17NO2 The following contents are mentioned in the article:

ML2 (M = Cu, HL = I (R = H, R1 = CHMe2, Ph, CMe3 or R = Ph, RI = Me); M = Zn, Co, Ni, FeCl, R = H, R1 = CHMe2) and I were prepared ML2 (M = Cu, Zn, Ni; R = H, R1 = CHMe2) were analyzed by x-ray diffraction studies [monoclinic, space group P21, A2, A2, Z = 4, 2, 2, Rw = 0.078, 0.074, 0.060, resp.]. L coordinates through the hydrooxazole N and phenolato O atoms. CuL2 and NiL2 have a distorted square planar configuration whereas ZnL2 has a distorted tetrahedral configuration. ML2 were characterized by IR and mass spectra. This study involved multiple reactions and reactants, such as (S)-2-(4-(tert-Butyl)-4,5-dihydrooxazol-2-yl)phenol (cas: 135948-04-8Formula: C13H17NO2).

(S)-2-(4-(tert-Butyl)-4,5-dihydrooxazol-2-yl)phenol (cas: 135948-04-8) belongs to oxazolidine derivatives. Oxazolidine-based compounds are well-known chiral auxiliaries and strategic molecular moieties in chemistry since they can effectively mask or mimic amino acid units or amino alcohols. Some reports highlighted again the effectiveness of oxazolidine-based compounds in driving the stereo- or diastereotopic outcome of chemical reactions.Formula: C13H17NO2

135948-04-8;(S)-2-(4-(tert-Butyl)-4,5-dihydrooxazol-2-yl)phenol;The future of 135948-04-8;New trend of C13H17NO2;function of 135948-04-8

Cobalt/Salox-Catalyzed Enantioselective C-H Functionalization of Arylphosphinamides was written by Yao, Qi-Jun; Chen, Jia-Hao; Song, Hong; Huang, Fan-Rui; Shi, Bing-Feng. And the article was included in Angewandte Chemie, International Edition on June 20,2022.Reference of 163165-92-2 The following contents are mentioned in the article:

Previous methods on Co(III)-catalyzed asym. C-H activation rely on the use of tailor-made cyclopentadienyl-ligated Co(III) complexes, which require lengthy steps for the preparation Herein, the authors report an unprecedented enantioselective C-H functionalization enabled by a simple Co/salicyloxazoline (Salox) catalysis. The chiral Salox ligands can be easily prepared in one step from salicylonitrile and chiral amino alcs. A broad range of P-stereogenic compounds were synthesized in high yields with excellent enantioselectivities (45 examples, up to 99% yield and >99% ee). The isolation and characterization of several intermediates provided insights into the generation of active catalytic Co species, the action of Salox, and the mode of stereocontrol. This study involved multiple reactions and reactants, such as (S)-2-(4-Benzyl-4,5-dihydrooxazol-2-yl)phenol (cas: 163165-92-2Reference of 163165-92-2).

(S)-2-(4-Benzyl-4,5-dihydrooxazol-2-yl)phenol (cas: 163165-92-2) belongs to oxazolidine derivatives. Oxazolidine-based compounds have started to attract attention also in the medicinal and materials chemistry fields. Chiral oxazolidines are widely used as chiral auxiliaries, chiral ligands, protecting and/or directing groups in a variety of asymmetric transformations, thanks also to their easy cleavage or their further elaboration possibilities.Reference of 163165-92-2

163165-92-2;(S)-2-(4-Benzyl-4,5-dihydrooxazol-2-yl)phenol;The future of 163165-92-2;New trend of C16H15NO2;function of 163165-92-2